Steve Horvath - UCLA
Epigenetic clock analysis of race/ethnicity, sex, and chronic diseases
Date: 12/08/2016 (Thu)
Time: 3:30pm- 5:00pm
Location: Seminar will be held on-site: Gross Hall 270
Organizer: Dan Belsky
Meeting Schedule: Login or email the organizer to schedule a meeting.
All meetings will be held in the same location as the seminar unless otherwise noted.
9:00am - Breakfast w/ Costello & Copeland
9:30am - Breakfast w/ Costello & Copeland
10:00am - Breakfast w/ Costello & Copeland
10:30am - Emma Zang
11:00am - Kraus & Belsky
11:30am - Kraus & Belsky
12:00pm - Lunch w/ Snyder-Mackler, Noppert et al.
12:30pm - Lunch w/ Snyder-Mackler, Noppert et al.
1:00pm - Lunch w/ Snyder-Mackler, Noppert et al.
1:30pm - Giovanna Merli
2:00pm - Scott Lynch
2:30pm - Elizabeth Frankenberg
3:00pm - Seminar Prep
3:30pm - Seminar Presentation (3:30pm to 5:00pm)
Additional Comments: Abstract: Epigenetic biomarkers of aging (the “epigenetic clock”) have the potential to address puzzling findings surrounding mortality rates and incidence of cardio-metabolic disease such as: (1) women consistently exhibiting lower mortality than men despite having higher levels of morbidity; (2) racial/ethnic groups having different mortality rates even after adjusting for socioeconomic differences; (3) the black/white mortality cross-over effect in late adulthood; and (4) Hispanics in the United States having a longer life expectancy than Caucasians despite having a higher burden of traditional cardio-metabolic risk factors. The epigenetic clock method has been used in many applications including studying aging effects associated with obesity, Down syndrome, cognitive decline, HIV infection, neurodegenerative diseases, and centenarian status. Electronic copy of papers Article: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1030-0 Article: https://genomebiology.biomedcentral.com/articles/10.1186/gb-2013-14-10-r115