David A Bennett - Rush University Medical Center, Neurological Sciences

Mixed Pathology, Risk Factors, Resilience, and Personalized Medicine for Alzheimer's Dementia

    Date:  01/13/2022 (Thu)

    Time:  3:30pm- 5:00pm

    Location:  This seminar will be held remotely via Zoom. (Please sign in to see the link.)

    Organizer:  Avshalom Caspi

Meeting Schedule: Login or email the organizer to schedule a meeting.

    Meetings will be held via Zoom unless otherwise noted.

    Meeting location:  (Please sign in to see the link.)

    1:30pm - Michael Lutz, Sheng Luo, Andy Liu

    2:00pm - Heather Whitson

    3:00pm - Seminar Prep

    3:30pm - Seminar Presentation (3:30pm to 5:00pm)

    Additional Comments:  Will introduce you to two prospective analytic cohort studies of aging and dementia in which all participants agree to donate brain, spinal cord, muscle and nerve, and more recently skin, fat, and bone, at the time of death. He will demonstrate how loss of cognition is a complex function of numerous brain pathologies that add to and interact with numerous indices of resilience. Finally, leveraging a unique platform of more than 50 induced pluripotent stem cells (iPSCs) from autopsied study participants, he will illustrate a path to personalized medicine for AD and resilience.